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Is doxylamine succinate bad for your liver? No evidence of enzyme induction has been found in humans. Doxylamine succinate causes liver damage in mice; this effect may be related to its hepatocarcinogenicity. Doxylamine succinate is considered not to be genotoxic.
What happens after 48 hours of no sleep? The effects of sleep deprivation intensify the longer a person stays awake. After going without sleep for 48 hours, a person's cognitive performance will worsen, and they will become very fatigued. At this point, the brain will start entering brief periods of complete unconsciousness, also known as microsleep.
Which is better for sleep diphenhydramine or doxylamine? Doxylamine succinate is one of the most sedating antihistamines available over-the-counter (stronger than diphenhydramine). A single dose causes rapid and marked drowsiness in the vast majority of individuals. Unlike diphenhydramine, most people don't develop a tolerance to the sedating effects of doxylamine succinate.
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