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How does azathioprine help lupus? It suppresses the immune system by interfering with DNA synthesis (the creation of DNA molecules). It is used in dermatomyositis, systemic lupus erythematosus (lupus), inflammatory bowel disease, vasculitis (inflammation of the blood vessels), rheumatoid arthritis, as well as other inflammatory conditions.
Why are steroids given in nephrotic syndrome? Nephrotic syndrome is a condition where the kidneys leak protein from the blood into the urine. Most children, with nephrotic syndrome, respond to corticosteroid drugs (prednisone, prednisolone) reducing the risk of serious infection.
How do steroids help nephrotic syndrome? Corticosteroids (prednisone), cyclophosphamide, and cyclosporine are used to induce remission in nephrotic syndrome. Diuretics are used to reduce edema. Prednisone in short courses from 12-20 weeks' duration remains the mainstay of treatment for patients with minimal-change disease.
Is nephrotic syndrome reversible? Reversible Renal Failure in the Nephrotic Syndrome. Acute, usually reversible, renal failure has been observed in patients with normal or minimally altered glomeruli on renal biopsy. Although acute renal failure is uncommon, GFR is reduced concurrently with nephrotic syndrome in approximately 30% of children and adults
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